Manufacturer:

          Glaxosmithkline

Contents:

          Salbutamol sulfate

Indications:

          Tab/Syr Relief of bronchospasm in bronchial asthma, chronic bronchitis & emphysema. Tab Also for maintenance therapy in premature labour. Inhalation soln Status asthmaticus & other forms of bronchospasm. Evohaler Relief & prevention of asthma symptoms. Nebules Routine management of chronic bronchospasm & in the treatment of acute severe asthma (status asthmaticus). Inj Severe bronchospasm & status asthmaticus; management of uncomplicated premature labour in the last trimester of pregnancy.

Contraindications:

          Threatened abortion during 1st or 2nd trimesters of pregnancy. Toxaemia of pregnancy, antepartum haemorrhage, placenta praevia.

Special Precautions:

          Thyrotoxicosis; CV disease; diabetes. Monitor serum K level in acute severe asthma. Patients known to have received large doses of other sympathomimetics. Avoid soln or mist from entering the eye (resp soln & nebules). Monitor development of elevated serum lactate & consequent metabolic acidosis (IV & nebules). Administer oxygen concurrently w/ parenteral Ventolin. Inhaled salbutamol prep are not appropriate for managing premature labour. Pregnancy & lactation.

Dosage:

          Tab Adult 4 mg. Childn > 12 yr 2-4 mg, 6-12 yr 2 mg, 2-6 yr 1-2 mg. To be taken tds-qds. Syr Adult 2 tsp. Childn >12 yr 1-2 tsp, 6-12 yr 1 tsp, 2-6 yr 1/2-1 tsp. To be given tds-qds. Inhalation soln Intermittent administration Adult 0.5-1 mL diluted to a final vol of 2-2.5 mL nebulised & administered over 10 min. Or 2 mL of undiluted soln over 3-5 min. Childn <12 yr 0.5 mL diluted to a final vol of 2-2.5 mL. Some childn may require higher doses up to 1 mL. Continuous administration Dilute soln to contain 50-100 mcg salbutamol/mL & administer as an aerosol at rate of 1-2 mg/hr. Evohaler Relief of acute bronchospasm Adult & childn 100-200 mcg. Prevention of allergen or exercise-induced bronchospasm Adult 200 mcg before challenge. Childn 100-200 mcg before challenge. Chronic therapy Adult & childn 200 mcg, up to qds. Nebules 2.5 mg, may be increased to 5 mg. Treatment may be repeated qds. IV infusion Adult Severe bronchospasm & status asthmaticus Initially 5 mcg/min, adjusted according to response. Usual dose range: 3-20 mcg/min, but patients w/ resp failure may require higher doses. Management of premature labour Initially 10 mcg/min, rate increased gradually at 10-min intervals until contractions diminish then increase rate slowly until contractions cease. Usual dose range: 10-45 mcg/min. Maintain rate for 1 hr after contractions have stopped, then gradually reduce by 50% at 6-hrly intervals. Treatment may be continued orally w/ 4 mg tds-qds

Class:

          Antiasthmatic & COPD Preparations

Presentation/Packing:

          Ventolin syrup - Ventolin 2 mg/5 mL x 60 mL x 1's

Details:

          MyPhuocPharmacy – (08) 62581003