ZITHROMAX
Code : Zit01
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Zithromax/Zitromax
200 mg/5 ml x 15 ml
Zithromax/Zitromax 500 mg x 3 tablets.
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ZITHROMAX
Manufacturer:
Pfizer
Contents:
Azithromycin
Indications:
Upper & lower resp tract infections,
odontostomatological infections, skin & soft tissue infections, acute
otitis media, STD due to Chlamydia trachomatis, chancroid due to Haemophilus
ducreyi & uncomplicated genital infection due to non-multiresistant
Neisseria gonorrhoea. Prophylaxis (alone or in combination w/ rifabutin)
against Mycobacterium avium-intracellulare complex (MAC) infection prevalent in
patients w/ advanced HIV. IV vial Community-acquired pneumonia (CAP) &
pelvic inflammatory disease (PID) in patients who require initial IV therapy.
Contraindications:
Hypersensitivity to any of the ingredients, Known hypersensitivity to azithromycin,
erythromycin, macrolides or ketolides. Hereditary fructose intolerance,
glucose-galactose malabsorption or saccharase-isomaltase deficiency.
Special Precautions:
Severe renal impairment (GFR <10 mL/min).
Significant hepatic disease. Avoid co-administration w/ ergot
derivatives. Observe signs of superinfection w/ nonsusceptible organisms
including fungi. Consider Clostridium difficile-associated
diarrhea in patients who present diarrhea following therapy. Prolonged
cardiac repolarization & QT interval. Pregnancy & lactation. Powd for oral susp Diabetic patients. IV vial Do not administer as IV bolus or IM inj.
Dosage:
Tab/Powd for oral susp Adult Treatment of STD due to
Chlamydia trachomatis or susceptible Neisseria gonorrhoea 1000 mg as a single
dose. Prophylaxis against MAC infections in patients w/ HIV 1200 mg once/wk.
All other indications 1500 mg to be given as 500 mg daily for 3 days. Childn
Max: 1500 mg. Total dose: 30 mg/kg. Tab >45 kg Adult dose. Ped streptococcal
pharyngitis Powd for oral susp >45 kg Adult dose; 36-45 kg 400 mg; 26-35 kg
300 mg; 15-25 kg 200 mg; <15 kg 10 mg/kg. Doses to be taken once daily on
days 1-3 or alternatively taken as a single dose on day 1, then ½ the daily
dose on days 2-5. Elderly Adult dose. IV infusion Adult CAP 500 mg as a single
daily IV dose for at least 2 days, followed by oral azithromycin 500 mg as a
single daily dose to complete a 7- to 10-day course of therapy. PID 500 mg as a
single daily dose for 1-2 days, followed by oral azithromycin 250 mg as a
single daily dose to complete a 7-day course of therapy.
Class:
Macrolides
Presentation/Packing:
Zithromax/Zitromax
200 mg/5 ml x 15 ml
Zithromax/Zitromax 500 mg x 3 tablets.
Details:
MyPhuocPharmacy – (08) 62581003
Azithromycin
Tab/Powd for oral susp Adult Treatment of STD due to
Chlamydia trachomatis or susceptible Neisseria gonorrhoea 1000 mg as a single
dose. Prophylaxis against MAC infections in patients w/ HIV 1200 mg once/wk.
All other indications 1500 mg to be given as 500 mg daily for 3 days. Childn
Max: 1500 mg. Total dose: 30 mg/kg. Tab >45 kg Adult dose. Ped streptococcal
pharyngitis Powd for oral susp >45 kg Adult dose; 36-45 kg 400 mg; 26-35 kg
300 mg; 15-25 kg 200 mg; <15 kg 10 mg/kg. Doses to be taken once daily on
days 1-3 or alternatively taken as a single dose on day 1, then ½ the daily
dose on days 2-5. Elderly Adult dose. IV infusion Adult CAP 500 mg as a single
daily IV dose for at least 2 days, followed by oral azithromycin 500 mg as a
single daily dose to complete a 7- to 10-day course of therapy. PID 500 mg as a
single daily dose for 1-2 days, followed by oral azithromycin 250 mg as a
single daily dose to complete a 7-day course of therapy.
Updating
Severe renal impairment (GFR <10 mL/min).
Significant hepatic disease. Avoid co-administration w/ ergot
derivatives. Observe signs of superinfection w/ nonsusceptible organisms
including fungi. Consider Clostridium difficile-associated
diarrhea in patients who present diarrhea following therapy. Prolonged
cardiac repolarization & QT interval. Pregnancy & lactation. Powd for oral susp Diabetic patients. IV vial Do not administer as IV bolus or IM inj.