Manufacturer:

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          Merck Sharp & Dohme

Contents:

          Enalapril maleate

Indications:

          Treatment of all grades of essential HTN; renovascular HTN, heart failure. Prevention of symptomatic heart failure & coronary ischaemic events in patient w/ left ventricular dysfunction.

Contraindications:

          History of angioneurotic edema related to previous treatment w/ an ACE inhibitor; hereditary or idiopathic angioedema. Childn.

Special Precautions:

          Vol-depleted patients; ischemic heart or cerebrovascular disease; aortic stenosis or hypertrophic cardiomyopathy; renal insufficiency; bilateral renal artery stenosis or artery stenosis to a solitary kidney; diabetes; hemodialysis patients. Patients undergoing major surgery or during anesth w/ agents that produce hypotension. Pregnancy & lactation.

Dosage:

          Essential HTN Mild: Initially 10 mg/day. Moderate or severe: Initially 20 mg/day. Maintenance: 20 mg once daily. Max: 40 mg daily. Renovascular HTN Initially ≤5 mg. Maintenance: 20 mg once daily. Concomitant diuretic therapy in HTN Discontinue diuretic 2-3 days prior to initiation of therapy. If this is not possible, initial dose should be ≤5 mg, adjust thereafter. Renal impairment CrCl <80->30 mL/min 5-10 mg; ≤30->10 mL/min 2.5-5 mg; ≤10 mL/min 2.5 mg on dialysis days. Heart failure/asymptomatic left ventricular dysfunction Initially 2.5 mg. Usual maintenance dose: 20 mg daily given in single or 2 divided doses.

Class:

          ACE Inhibitors/Direct Renin Inhibitors

Presentation/Packing:

          Renitec 5 mg x 30 tabs
          Renitec 10 mg x 30 tabs
          Renitec 20 mg x 30 tabs

Details:

          MyPhuocPharmacy – (08) 62581003