Manufacturer:

          GlaxoSmithKline

Contents:

          Adefovir dipivoxil

Indications:

          Treatment of chronic hepatitis B in adults w/ evidence of hepatitis B viral replication & either evidence of persistent elevations in serum aminotransferases or histologically active disease. Provides reductions of viral replication & improvements in liver function in a limited number of chronic hepatitis B patients w/ genotypic evidence of lamivudine resistance including compensated or decompensated liver disease & HIV co-infection.

Contraindications:

          Hypersensitivity to any of the ingredients, Lactation

Special Precautions:

          Should not be administered concurrently w/ tenofovir DF or tenofovir DF-containing products including Truvada (emtricitabine/tenofovir DF combination tab) & Atripla (efavirenz/emtricitabine/tenofovir DF combination tab). Renal impairment; advanced liver disease or cirrhosis; patients (esp obese women) w/ hepatomegaly, hepatitis or other known risk factors for liver disease; HIV co-infection; congenital carnitine deficiency. Pregnancy. Childn & adolescent <18 yr. Elderly >65 yr.

Dosage:

          Adult 18-65 yr 10 mg once daily. Renal impairment CrCl 30-49 mL/min 10 mg 48 hrly; 10-29 mL/min 10 mg 72 hrly. Haemodialysis patients 10 mg every 7 days following dialysis.

Class:

          Antivirals

Presentation/Packing:

          Hepsera tab 10 mg x 30's

Details:

          MyPhuocPharmacy – (08) 62581003