APROVEL

Manufacturer:

Sanofi-Aventis

Contents:

Irbesartan

Indications:

Essential HTN. Treatment of renal disease in patients w/ HTN & type 2 DM as part of an antihypertensive drug regimen.

Contraindications:

Pregnancy & lactation.

Special Precautions:

Increased risk of severe hypotension in patients w/ renal artery stenosis. Periodic monitoring of K & serum creatinine in patients w/ renal impairment. Monitoring of serum K in patients, suffering from heart failure. Patients w/ recent kidney transplantation, primary aldosteronism, aortic or mitral stenosis, obstructive hypertrophic cardiomyopathy, ischaemic cardiopathy or ischaemic CV disease.

Dosage:

Initial & maintenance dose: 150 mg once daily. May be increased to 300 mg or other antihypertensive agents can be added. In vol-depleted patients, correct prior to administration. Elderly >75 yr & haemodialysis patients Consider initiating w/ 75 mg. Hypertensive type 2 diabetic patients Initially 150 mg once daily. Maintenance: 300 mg once daily.

Class:

Angiotensin II Antagonists

Presentation/Packing:

Aprovel film-coated tablet

Aprovel 150 mg x 28's

Aprovel 300 mg x 28's

Details:

MyPhuocPharmacy – (08) 62581003

Irbesartan

Initial & maintenance dose: 150 mg once daily. May be increased to 300 mg or other antihypertensive agents can be added. In vol-depleted patients, correct prior to administration. Elderly >75 yr & haemodialysis patients Consider initiating w/ 75 mg. Hypertensive type 2 diabetic patients Initially 150 mg once daily. Maintenance: 300 mg once daily.

Updating

Increased risk of severe hypotension in patients w/ renal artery stenosis. Periodic monitoring of K & serum creatinine in patients w/ renal impairment. Monitoring of serum K in patients, suffering from heart failure. Patients w/ recent kidney transplantation, primary aldosteronism, aortic or mitral stenosis, obstructive hypertrophic cardiomyopathy, ischaemic cardiopathy or ischaemic CV disease.

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